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Post# A1004224

mRNA Display-based Antibody Discovery

Posted on: Tuesday, 26 December, 2023  09:18
Updated On: Tuesday, 26 December, 2023  09:18
Expires On: Monday, 21 September, 2026  15:18
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mRNA Display for Antibody Discovery
mRNA display technology is to use genetic engineering technology to synthesize or extract antibody genes and transcribe them into mRNA in vitro, connect the mRNA with the antibody obtained in the process of in vitro translation through puromycin, and then reverse transcribe to form a ternary complex and combine it with the target protein, complete the screening of antibody under mRNA display, and obtain high affinity and high specificity target antibody through multiple rounds of elutriation. Based on mRNA display technology, it can realize the discovery of many kinds of antibodies, including mouse monoclonal antibody, rabbit monoclonal antibody, chicken monoclonal antibody and all human monoclonal antibody.http://www.aspiregene.com/mrna-display-based-antibody-discovery.html »

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